Chapter 2: Infection Case 2.1 The lymphocytes showing atypical morphology ('atypical lymphocytosis') Case 2.2 Herpes Zoster Case 2.8 Pseudohyphae Case 2.9 Heavy infestation with Plasmodium falciparum Case 2.10 Characteristic ova of Schistosoma mansoni
Chapter 3: Immunodeficiency Case 3.5 Bacterial killing and sit of abnormalities in chronic granulomatous Case 3.5 Nitroblue tetrazolium (NBT) test Case 3.6 CH 50 plates Case 3.7 Oral hairy leucoplakia Case 3.7 Kaposi's sarcoma Case 3.7 Leucocyte adhesion deficiency disease Case 3.10 Acquired immune deficiency syndrome: Kaposi’s sarcoma
Chapter 4: Anaphylaxis and Allergy Case 4.1 Injections Case 4.2a Medic Alert bracelet Case 4.2b Self-injectable form of epinephrine Case 4.3 Angioedema Case 4.4 Acute conjunctivitis Case 4.5 Skin testing with dilutions of grass pollen Case 4.8a A medical alert bracelet Case 4.8b A self-injectable form of adrenaline Case 4.10 Nettle rash Case 4.11 Typical urticaria Case 4.12 Extensive atopic eczema
Chapter 5: Autoimmunity Case 5.3 Family study of autoimmue disease Case 5.6 Lupus band test
Chapter 6: Lymphoproliferative Disorders Case 6.1 Blood film showed that most leucocytes were blasts Case 6.1 Acute lymphoblastic leukaemia Case 6.2 Chronic lymphocytic leukaemia Case 6.3 Sézary syndrome Case 6.5 Enlarged hilar lymph nodes, unlike case Case 6.5 Stage 2 Hodgkin's disease Case 6.7 Multiple myeloma Case 6.7 Myeloma cells. Case 6.7 IgG of kappa type. Case 6.7 Atypical plasma cells Case 6.7 Myeloma of bone
Chapter 7: Immune Manipulation Case 7.2 Chest X-ray Case 7.2 Antineutrophil antibody (cytoplasmic pattern): weakly positive at a titre of 1:40 (>1:640 at disease diagnosis). Case 7.3 Hands in RA and Histology of pannus Case 7.4 Development of coronary artery aneurysms
Chapter 8: Transplantation Case 8.1 Lymphocytic infiltration Case 8.2 Primary CMV infection Case 8.3 Acute myeloid leukaemia Case 8.4 Widespread erythematous maculopapular rash
Chapter 9: Kidney Diseases Case 9.2 Characteristics of membranous nephropathy Case 9.2 Sites of immune-complex deposition in humans. Case 9.4 Linear staining with IgG Case 9.5 Classical antineutrophil cytoplasmic antibodies Case 9.5 Renal histological appearance in microscopic polyangiitis Case 9.5 ANCA-associated, necrotizing crescentic glomerulonephritis. Case 9.7 Purpura Case 9.11 Serum electrophoresis showed a decreased gamma fraction with a monoclonal band Case 9.11 Immunofixation Case 9.11 Serum and urine showed an IgA Case 9.11 Monoclonal free lambda light chains in the urine Case 9.11 A bone marrow aspirate showed marked infiltration Case 9.11 Atypical plasma Case 9.11 Osteolytic lesions in the pelvis and skull Case 9.11 Myeloma kidney
Chapter 10: Joints and Muscles Case 10.2 Rheumatoid arthritis Case 10.2 Both hands were swollen and tender Case 10.2 Two subcutaneous nodules on the left elbow Case 10.2 Pannus Case 10.2 Rheumatoid arthritis Case 10.3 His joints were tender and he had subluxation of the metacarpophalangeal joints of both hands Case 10.3 Swan-neck deformities Case 10.3 X-rays showed erosions Case 10.4 Ankylosing spondylitis Case 10.4 Bony ankylosis between the lumbar vertabrae Case 10.5 Keratoderma blenorrhagica Case 10.5 Conjunctivitis Case 10.6 Behcet's syndrome Case 10.8 Bilateral, blotchy rash on her hands and thighs Case 10.8 Raynaud's phenomenon concurrently became much worse Case 10.8 Lupus band test Case 10.9 Facial rash Case 10.10 Hands Case 10.10 ANA (titre 1/160; speckled pattern) Case 10.10 Raynaud's phenomenon Case 10.10 Sclerodactyly Case 10.11 Sjögren's syndrome Case 10.12 Biopsy of an affected calf muscle Case 10.12 Histology of three types of vasculitis Case 10.13 Temporal artery
Chapter 11: Skin Diseases Case 11.2 Itchy rash Case 11.3 Contact dermatitis Case 11.3 Nickel dermatitis Case 11.4 Pempigus vulgaris Case 11.5 Swelling of his lips, eyes Case 11.6 Urticarial vasculitis Case 11.7 Papular rash Case 11.7 A warm sample of her serum contained a mixed cryoglobulin Case 11.7 Monoclonal IgM and polyclonal IgG. Case 11.7 Histology of a renal biopsy Case 11.7 Immunofluorescence Case 11.8 Chronic discoid lupus erythematosus Case 11.9 Raynaud's phenomenon Case 11.9 'Tiny pieces of chalk' Case 11.9 Atonic oesophagus Case 11.9 Sclerodactyly Case 11.9 Typical skin changes of scleroderma
Chapter 12: Eye Diseases
Chapter 13: Chest Diseases Case 13.1 Bilateral lower-lobe pneumonia Case 13.2 Chest X-ray Case 13.2 Mantoux test Case 13.3 Bilateral hilar lymphadenopathy Case 13.4 Pulmonary Fibrosis in Rheumatoid Arthritis: Bamboo lumbar spine in ankylosing spondylitis Case 13.5 X-ray changes gradually improved Case 13.7 Pulmonary Fibrosis in Rheumatoid Arthritis: High-resolution computed tomography scan Case 13.8 Echocardiogram which demonstrated aneurysms of the right and left anterior descending coronary arteries
Chapter 14: Gastrointestinal and Liver Diseases Case 14.2 Gastric parietal cell antibodies Case 14.8 Antimitochondrial antibodies
Chapter 15: Endocrinology and Diabetes Case 15.1 Exophthalmos
Chapter 16: Haematological Diseases Case 16.1 Yellow eyes Case 16.1 Blood film showed gross polychromasia Case 16.1 Reticulocyte count Case 16.1 Urinary haemosiderin Case 16.2 Blood film showed rouleaux formation Case 16.3 Cephalosporin-induced haemolytic anaemia Case 16.4 Spontaneous bruising Case 16.4 Scattered petechiae Case 16.4 Low platelet count
Chapter 17: Neuroimmunology Case 17.2 Perivenricular white matter lesions in MS
Chapter 18: Pregnancy Case 18.5 Low haemoglobin