FIFTH EDITION

Characteristic owl's eye intranuclear inclusion bodies in the kidney of a pateint with disseminated cytomegalovirus infection. Positive histology, as in this figure, is a very useful clue to the presence of CMV infection but serological confirmation should always be sought since production of antigen specific antibodies (IgG & IgM) are usually retained following transplantation. Reproduced with kind permission of Herriot R and Gray ES, New Engl J Med 1994;331:649.

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